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1Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling by Nicholas T. Ingolia and othersgenome-wide-analysis-in-vivo-of-translation-with-nucleotide-resolution-using-ribosome-profiling-by-nicholas-t-ingolia-and-others2026-10-202026-10-20
1Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes by Nicholas T. Ingolia and othersribosome-profiling-of-mouse-embryonic-stem-cells-reveals-the-complexity-and-dynamics-of-mammalian-proteomes-by-nicholas-t-ingolia-and-others2026-10-202026-10-20
1Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution by Sooncheol Lee and othersglobal-mapping-of-translation-initiation-sites-in-mammalian-cells-at-single-nucleotide-resolution-by-sooncheol-lee-and-others2026-10-202026-10-20
1The translational landscape of mTOR signalling steers cancer initiation and metastasis by Andrew C. Hsieh and othersthe-translational-landscape-of-mtor-signalling-steers-cancer-initiation-and-metastasis-by-andrew-c-hsieh-and-others2026-10-202026-10-20
1Dynamics of ribosome scanning and recycling revealed by translation complex profiling by Stuart K. Archer and othersdynamics-of-ribosome-scanning-and-recycling-revealed-by-translation-complex-profiling-by-stuart-k-archer-and-others2026-10-202026-10-20
1In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition by Carmen C. Robinett and othersin-vivo-localization-of-dna-sequences-and-visualization-of-large-scale-chromatin-organization-using-lac-operator-repressor-recognition-by-carmen-c-robinett-and-others2026-10-202026-10-20
1Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system by Baohui Chen and othersdynamic-imaging-of-genomic-loci-in-living-human-cells-by-an-optimized-crispr-cas-system-by-baohui-chen-and-others2026-10-202026-10-20
1Chickens possess centromeres with both extended tandem repeats and short non-tandem-repetitive sequences by Wei-Hao Shang and otherschickens-possess-centromeres-with-both-extended-tandem-repeats-and-short-non-tandem-repetitive-sequences-by-wei-hao-shang-and-others2026-10-202026-10-20
1Birth, evolution, and transmission of satellite-free mammalian centromeric domains by Solomon G. Nergadze and othersbirth-evolution-and-transmission-of-satellite-free-mammalian-centromeric-domains-by-solomon-g-nergadze-and-others2026-10-202026-10-20
1Chromosome Engineering Allows the Efficient Isolation of Vertebrate Neocentromeres by Wei-Hao Shang and otherschromosome-engineering-allows-the-efficient-isolation-of-vertebrate-neocentromeres-by-wei-hao-shang-and-others2026-10-202026-10-20
1Genetic control of the cell-division cycle in yeast. I. Detection of mutants by Leland H. Hartwell and othersgenetic-control-of-the-cell-division-cycle-in-yeast-i-detection-of-mutants-by-leland-h-hartwell-and-others2026-10-202026-10-20
1Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe by Paul Nurse and othersgenetic-control-of-the-cell-division-cycle-in-the-fission-yeast-schizosaccharomyces-pombe-by-paul-nurse-and-others2026-10-202026-10-20
1The Protein Kinase Kin4 Inhibits Exit from Mitosis in Response to Spindle Position Defects by Katharine E. D'Aquino and othersthe-protein-kinase-kin4-inhibits-exit-from-mitosis-in-response-to-spindle-position-defects-by-katharine-e-d-aquino-and-others2026-10-202026-10-20
1Elm1 kinase activates the spindle position checkpoint kinase Kin4 by Ayse Koca Caydasi and otherselm1-kinase-activates-the-spindle-position-checkpoint-kinase-kin4-by-ayse-koca-caydasi-and-others2026-10-202026-10-20
1Centrosome misorientation reduces stem cell division during aging by Jun Cheng and otherscentrosome-misorientation-reduces-stem-cell-division-during-aging-by-jun-cheng-and-others2026-10-202026-10-20
1Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells by Hebao Yuan and othersregulation-of-cyclin-a-localization-downstream-of-par-1-function-is-critical-for-the-centrosome-orientation-checkpoint-in-drosophila-male-germline-stem-cells-by-hebao-yuan-and-others2026-10-202026-10-20
1The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline by Mayu Inaba and othersthe-polarity-protein-baz-forms-a-platform-for-the-centrosome-orientation-during-asymmetric-stem-cell-division-in-the-drosophila-male-germline-by-mayu-inaba-and-others2026-10-202026-10-20
1Bacterial persistence as a phenotypic switch by Nathalie Q. Balaban and othersbacterial-persistence-as-a-phenotypic-switch-by-nathalie-q-balaban-and-others2026-10-202026-10-20
1Nucleosome plasticity is a critical element of chromatin liquid-liquid phase separation and multivalent nucleosome interactions by Stephen E. Farr and othersnucleosome-plasticity-is-a-critical-element-of-chromatin-liquid-liquid-phase-separation-and-multivalent-nucleosome-interactions-by-stephen-e-farr-and-others2026-10-202026-10-20
1Organization of Chromatin by Intrinsic and Regulated Phase Separation by Bryan A. Gibson and othersorganization-of-chromatin-by-intrinsic-and-regulated-phase-separation-by-bryan-a-gibson-and-others2026-10-202026-10-20

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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