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1PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems by Ahmadreza Ghaffarizadeh and othersphysicell-an-open-source-physics-based-cell-simulator-for-3-d-multicellular-systems-by-ahmadreza-ghaffarizadeh-and-others2026-10-202026-10-20
1scGen predicts single-cell perturbation responses by Mohammad Lotfollahi and othersscgen-predicts-single-cell-perturbation-responses-by-mohammad-lotfollahi-and-others2026-10-202026-10-20
1Adaptive protein evolution at the Adh locus in Drosophila by John H. McDonald and Martin Kreitmanadaptive-protein-evolution-at-the-adh-locus-in-drosophila-by-john-h-mcdonald-and-martin-kreitman2026-10-202026-10-20
1Phenotypic Plasticity in Drosophila Pigmentation Caused by Temperature Sensitivity of a Chromatin Regulator Network by Jean-Michel Gibert and othersphenotypic-plasticity-in-drosophila-pigmentation-caused-by-temperature-sensitivity-of-a-chromatin-regulator-network-by-jean-michel-gibert-and-others2026-10-202026-10-20
1Progressive Loss of Function in a Limb Enhancer during Snake Evolution by Evgeny Z. Kvon and othersprogressive-loss-of-function-in-a-limb-enhancer-during-snake-evolution-by-evgeny-z-kvon-and-others2026-10-202026-10-20
1Unpredictable evolution in a 30-year study of Darwin's finches by Peter R. Grant and B. Rosemary Grantunpredictable-evolution-in-a-30-year-study-of-darwin-s-finches-by-peter-r-grant-and-b-rosemary-grant2026-10-202026-10-20
1Introns are mediators of cell response to starvation by Julie Parenteau and othersintrons-are-mediators-of-cell-response-to-starvation-by-julie-parenteau-and-others2026-10-202026-10-20
1Excised linear introns regulate growth in yeast by Jeffrey T. Morgan and othersexcised-linear-introns-regulate-growth-in-yeast-by-jeffrey-t-morgan-and-others2026-10-202026-10-20
1Evolution of high mutation rates in experimental populations of E. coli by Paul D. Sniegowski and othersevolution-of-high-mutation-rates-in-experimental-populations-of-e-coli-by-paul-d-sniegowski-and-others2026-10-202026-10-20
1Running with the Red Queen: host-parasite coevolution selects for biparental sex by Levi T. Morran and othersrunning-with-the-red-queen-host-parasite-coevolution-selects-for-biparental-sex-by-levi-t-morran-and-others2026-10-202026-10-20
1Import of stably folded proteins into peroxisomes by P. A. Walton and othersimport-of-stably-folded-proteins-into-peroxisomes-by-p-a-walton-and-others2026-10-202026-10-20
1Golgi maturation visualized in living yeast by Eugene Losev and othersgolgi-maturation-visualized-in-living-yeast-by-eugene-losev-and-others2026-10-202026-10-20
1Rab Conversion as a Mechanism of Progression from Early to Late Endosomes by Jochen Rink and othersrab-conversion-as-a-mechanism-of-progression-from-early-to-late-endosomes-by-jochen-rink-and-others2026-10-202026-10-20
1Myosin V Walks Hand-Over-Hand: Single Fluorophore Imaging with 1.5-nm Localization by Ahmet Yildiz and othersmyosin-v-walks-hand-over-hand-single-fluorophore-imaging-with-1-5-nm-localization-by-ahmet-yildiz-and-others2026-10-202026-10-20
1Myosin VI is an actin-based motor that moves backwards by A. L. Wells and othersmyosin-vi-is-an-actin-based-motor-that-moves-backwards-by-a-l-wells-and-others2026-10-202026-10-20
1Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation by Shu-ou Shan and othersconformational-changes-in-the-gtpase-modules-of-the-signal-reception-particle-and-its-receptor-drive-initiation-of-protein-translocation-by-shu-ou-shan-and-others2026-10-202026-10-20
1Anchoring a Plant Cytochrome P450 via PsaM to the Thylakoids in Synechococcus sp. PCC 7002: Evidence for Light-Driven Biosynthesis by Lærke Münter Lassen and othersanchoring-a-plant-cytochrome-p450-via-psam-to-the-thylakoids-in-synechococcus-sp-pcc-7002-evidence-for-light-driven-biosynthesis-by-laerke-munter-lassen-and-others2026-10-202026-10-20
1Trienoic Fatty Acids Are Required to Maintain Chloroplast Function at Low Temperatures by Jean-Marc Routaboul and otherstrienoic-fatty-acids-are-required-to-maintain-chloroplast-function-at-low-temperatures-by-jean-marc-routaboul-and-others2026-10-202026-10-20
1Phosphate deprivation induces transfer of DGDG galactolipid from chloroplast to mitochondria by Juliette Jouhet and othersphosphate-deprivation-induces-transfer-of-dgdg-galactolipid-from-chloroplast-to-mitochondria-by-juliette-jouhet-and-others2026-10-202026-10-20
1Rapid electron exchange between surface-exposed bacterial cytochromes and Fe(III) minerals by Gaye F. White and othersrapid-electron-exchange-between-surface-exposed-bacterial-cytochromes-and-fe-iii-minerals-by-gaye-f-white-and-others2026-10-202026-10-20

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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