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1Stochastic Gene Expression in a Single Cell by Michael B. Elowitz and othersstochastic-gene-expression-in-a-single-cell-by-michael-b-elowitz-and-others2026-10-242026-10-24
1Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel by S. A. Seoh and othersvoltage-sensing-residues-in-the-s2-and-s4-segments-of-the-shaker-k-plus-channel-by-s-a-seoh-and-others2026-10-242026-10-24
1Crystal structure of a mammalian voltage-dependent Shaker family K+ channel by Stephen B. Long and otherscrystal-structure-of-a-mammalian-voltage-dependent-shaker-family-k-plus-channel-by-stephen-b-long-and-others2026-10-242026-10-24
1Biophysical and molecular mechanisms of Shaker potassium channel inactivation by Toshinori Hoshi and othersbiophysical-and-molecular-mechanisms-of-shaker-potassium-channel-inactivation-by-toshinori-hoshi-and-others2026-10-242026-10-24
1Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB by William N. Zagotta and othersrestoration-of-inactivation-in-mutants-of-shaker-potassium-channels-by-a-peptide-derived-from-shb-by-william-n-zagotta-and-others2026-10-242026-10-24
1Precise nanometer localization analysis for individual fluorescent probes by Russell E. Thompson and othersprecise-nanometer-localization-analysis-for-individual-fluorescent-probes-by-russell-e-thompson-and-others2026-10-242026-10-24
1Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia by Qing Wang and otherscardiac-sodium-channel-mutations-in-patients-with-long-qt-syndrome-an-inherited-cardiac-arrhythmia-by-qing-wang-and-others2026-10-242026-10-24
1Long-QT syndrome-related sodium channel mutations probed by the dynamic action potential clamp technique by Géza Berecki and otherslong-qt-syndrome-related-sodium-channel-mutations-probed-by-the-dynamic-action-potential-clamp-technique-by-geza-berecki-and-others2026-10-242026-10-24
1The skeletal muscle chloride channel in dominant and recessive human myotonia by Manuela C. Koch and othersthe-skeletal-muscle-chloride-channel-in-dominant-and-recessive-human-myotonia-by-manuela-c-koch-and-others2026-10-242026-10-24
1Mutations in dominant human myotonia congenita drastically alter the voltage dependence of the ClC-1 chloride channel by Michael Pusch and othersmutations-in-dominant-human-myotonia-congenita-drastically-alter-the-voltage-dependence-of-the-clc-1-chloride-channel-by-michael-pusch-and-others2026-10-242026-10-24
1The muscle chloride channel ClC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia by Caterina Saviane and othersthe-muscle-chloride-channel-clc-1-has-a-double-barreled-appearance-that-is-differentially-affected-in-dominant-and-recessive-myotonia-by-caterina-saviane-and-others2026-10-242026-10-24
1Robustness in simple biochemical networks by Naama Barkai and Stanislas Leiblerrobustness-in-simple-biochemical-networks-by-naama-barkai-and-stanislas-leibler2026-10-242026-10-24
1Experimental Test of Connector Rotation during DNA Packaging into Bacteriophage phi29 Capsids by Thorsten Hugel and othersexperimental-test-of-connector-rotation-during-dna-packaging-into-bacteriophage-phi29-capsids-by-thorsten-hugel-and-others2026-10-242026-10-24
1Energy, Life, and ATP by Paul D. Boyerenergy-life-and-atp-by-paul-d-boyer2026-10-242026-10-24
1Direct observation of base-pair stepping by RNA polymerase by Elio A. Abbondanzieri and othersdirect-observation-of-base-pair-stepping-by-rna-polymerase-by-elio-a-abbondanzieri-and-others2026-10-242026-10-24
1Zoological Philosophy by Jean-Baptiste Lamarckzoological-philosophy-by-jean-baptiste-lamarck2026-10-242026-10-24
1Contributions to the Theory of Natural Selection by Alfred Russel Wallacecontributions-to-the-theory-of-natural-selection-by-alfred-russel-wallace2026-10-242026-10-24
1Essays upon Heredity and Kindred Biological Problems by August Weismannessays-upon-heredity-and-kindred-biological-problems-by-august-weismann2026-10-242026-10-24
1High-density mapping of single-molecule trajectories with photoactivated localization microscopy by Suliana Manley and othershigh-density-mapping-of-single-molecule-trajectories-with-photoactivated-localization-microscopy-by-suliana-manley-and-others2026-10-242026-10-24
1The structural basis of ribosome activity in peptide bond synthesis by Poul Nissen and othersthe-structural-basis-of-ribosome-activity-in-peptide-bond-synthesis-by-poul-nissen-and-others2026-10-242026-10-24

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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