That makes Ciro Santilli most mad about this film is the fact that the dude was passionate about writing, and when he became a genius, rather than write the best novels ever written, he decided instead to play the stock market instead. This paints an accurate picture of 2020's society, where finance jobs make infinitely more money than other real engineering jobs, and end up attracting much of the talent.
Another enraging thing is how his girlfriend starts liking him again once he is a genius, and instead of telling her to fuck off, he stays with her.
The other really bad thing is the ending. He fixed the drug by himself? He scared off De Niro just like that?