= A. Armulik
{c}
<A. Armulik> investigated how <pericytes> regulate the <blood-brain barrier>. In the 2010 mouse study, pericyte-deficient mutants showed increased passage of tracers across brain vessels. The increased permeability involved endothelial <transcytosis>; the study also linked <pericytes> to endothelial gene-expression patterns and polarization of astrocyte end-feet.<Pericytes regulate the blood–brain barrier by A. Armulik and others>[Abstract: pericyte-deficient mice, tracer permeability, transcytosis and astrocyte polarization]{ref}
This makes an important mechanistic distinction: a barrier depends on regulated transport through cells as well as seals between cells. Measuring tracer escape and identifying the route of escape answer different experimental questions. The primary paper identifies the author as Annika Armulik.
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