A. Gow (source code)
= A. Gow
{c}
<A. Gow> is the first author of a 1999 study testing the function of <Claudin-11> in <myelin> and between <Sertoli cells>. Mice lacking the corresponding <gene> had slowed nerve conduction and reproductive abnormalities. <Freeze-fracture microscopy> showed the absence of characteristic <tight junction> strands in the affected membrane structures.<CNS myelin and Sertoli cell tight junction strands are absent in Osp claudin-11 null mice by A. Gow and others>[Abstract; Cell 99, 649–659, 1999]{ref}
The structural observation narrows the interpretation of the whole-animal changes: a defined membrane component was missing where a particular junctional pattern normally occurs. Absence of those <tight junction> strands should not be read as absence of all <myelin>. Combining molecular deletion, microscopy and physiological measurements connected <Claudin-11> with junction formation in two different tissue settings.<CNS myelin and Sertoli cell tight junction strands are absent in Osp claudin-11 null mice by A. Gow and others>[Abstract: myelin/Sertoli junctional strands and neurological/reproductive phenotypes]{ref}
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