Adenosine deaminase
= Adenosine deaminase
<Adenosine deaminase> catalyzes conversion of <adenosine> and <water> into <inosine> and <ammonia>. Its zinc-containing <active site> activates <water> and stabilizes the reacting configuration; <proton transfers> assist addition and leaving-group departure. Mutation kinetics constrain catalytic roles but do not uniquely locate every proton.