AGO4 (source code)

= AGO4
{c}

= ARGONAUTE4
{c}
{synonym}

An <Argonaute> <protein> participating in RNA-directed <chromatin> silencing.

In <Arabidopsis thaliana>, it associates with small interfering <RNAs> that help target <RNA-directed DNA methylation>. Sequence complementarity supplies specificity while partner <proteins> connect recognition to a <chromatin> modification rather than cleavage of every matching transcript. <ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation by Daniel Zilberman and others>[2003, AGO4-dependent methylation and silencing]{ref}