Alfred G. Gilman
= Alfred G. Gilman
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= A. G. Gilman
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<Alfred G. Gilman> coauthored purification and characterization of the regulatory component of adenylate cyclase. The work connects guanine-nucleotide-dependent regulation with production of the <second messenger> cyclic AMP.
Separating a regulatory component from the catalytic activity helps show how a signal can control an enzyme through another protein, rather than through direct substrate binding alone.<The regulatory component of adenylate cyclase. Purification and properties by P. C. Sternweis and others>[Primary publication: scientific topic and stated experimental result]{ref}
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