Anaphase-promoting complex
= Anaphase-promoting complex
{wiki}
= Anaphase-promoting complex/cyclosome
{synonym}
= APC/C
{c}
{synonym}
The <anaphase-promoting complex> is a regulated <ubiquitin ligase> that uses regulatory cofactors to target selected <cell cycle> <proteins> for destruction. Degradation of mitotic cyclins helps reset kinase activity during exit, while other substrates coordinate <chromosome> separation.