Anna Bafico (source code)

= Anna Bafico
{c}

<Anna Bafico> coauthored a mechanistic classification of <growth factors> and their <receptors>. The account treats a growth-factor family as a collection of related signal molecules with distinguishable <receptor> interactions, rather than as a single interchangeable stimulus.<Classification of Growth Factors and Their Receptors by Anna Bafico and Stuart A. Aaronson>[2003, Platelet-Derived Growth Factor Family and Fibroblast Growth Factor Family]{ref}

For example, related growth-factor chains can assemble into different dimers. Their <receptor> recognition and target-cell context help determine the biological response. This provides a useful bridge between <protein structure>, <signal transduction> and the regulation of <cell proliferation>.