= Antibody affinity
{title2=$K_d$}
<Antibody affinity> concerns one <paratope> binding one <epitope>. A <Fab fragment> supplies a single-site comparison. <Immunobiology: The Immune System in Health and Disease, 5th edition by Charles A. Janeway, Jr. and others/Glossary>[Immunobiology, 5th edition, Glossary: affinity, single-site binding]{ref} In the dilute <chemical equilibrium> model below, smaller <dissociation constant> $K_d$ means larger <antibody equilibrium occupancy> at the same free <antigen> <concentration>. State the <antigen>, <temperature> and <buffer solution>: a <dissociation constant> is not a context-free score. It does not alone specify how fast attachment or detachment occurs.
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