AP2 adaptor complex
= AP2 adaptor complex
{c}
The <AP2 adaptor complex> is a heterotetrameric adaptor that links selected plasma-membrane cargo to <clathrin> during <endocytosis>. Recognition of membrane <lipids> and cargo signals helps concentrate the machinery at appropriate locations. Internalization can reduce surface <receptor> abundance or return reusable components to an intracellular pool. AP2 acts at a different major location from the <AP1 adaptor complex>, despite the related coat-adaptor design. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 13, Transport into the Cell from the Plasma Membrane: clathrin-coated pits]{ref}