ATP synthesis reversible-balance concentration ratio (source code)

= ATP synthesis reversible-balance concentration ratio
{c}

For tight coupling of n downhill <protons> to m synthesized <ATP> per cycle, reversible balance gives $\Delta G_{\rm hyd}=(n/m)F\Delta p$ with a negative signed driving <proton-motive force>. Inserting $\Delta G_{\rm hyd}=\Delta G_{\rm hyd}^\circ+RT\ln(a_{\rm ADP}a_P/a_{\rm ATP})$ determines a concentration-ratio threshold. Finite net synthesis requires a driving margin, so balance alone does not specify the ratio in a working <cell>.