BLAST (source code)
= BLAST
{c}
{wiki=BLAST_(biotechnology)}
<BLAST>, the Basic Local Alignment Search Tool, searches a sequence database for high-scoring local similarities. It uses promising short matches to guide extension rather than exhaustively evaluating every possible alignment. Reported scores and expected counts help evaluate matches under a background model; they do not directly establish common function. A short conserved domain can produce a strong local match even when the complete <proteins> have different overall architectures. <Basic local alignment search tool by Stephen F. Altschul and others>[1990, word hits, extension and local similarity search]{ref}
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