Breakage-fusion-bridge cycle
= Breakage-fusion-bridge cycle
A repeating sequence of chromosome-end fusion, bridge formation and breakage during division. Inadequate end protection can perpetuate structural changes and copy-number alterations.
= Breakage-fusion-bridge cycle
A repeating sequence of chromosome-end fusion, bridge formation and breakage during division. Inadequate end protection can perpetuate structural changes and copy-number alterations.