BubR1 (source code)
= BubR1
{c}
A checkpoint regulator involved in attachment surveillance and inhibitory complexes controlling <anaphase-promoting complex>–<Cdc20>.
Checkpoint signalling restrains activation of the <anaphase-promoting complex> until suitable attachment conditions are reached. Inhibitory-complex assembly and the physical correction of attachments are related but distinct tasks, so one checkpoint readout need not establish normal <chromosome> alignment. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 17, The Spindle Assembly Checkpoint]{ref}
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