Cdc4 (source code)

= Cdc4
{c}

A substrate-recognition component of a <ubiquitin ligase> that recognizes phosphorylated <substrates>, including <Sic1>.

As part of an SCF-type assembly, it links a <substrate>’s <phosphorylation> state to ubiquitin-dependent turnover. The recognition step explains why adding <phosphate> can change <protein> lifetime without directly destroying the modified <protein>. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}