Cdt1
= Cdt1
{c}
A licensing factor that helps load <MCM2-7> onto origin <DNA> before helicase activation.
Licensing prepares origins before S-phase activation and must be restrained after replication begins. Separating preparation from firing helps prevent a genomic segment from being copied repeatedly in one <cell cycle>. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 17, Control of DNA Replication]{ref}