cGMP-dependent protein kinase (source code)

= cGMP-dependent protein kinase
{c}

A kinase regulated by cyclic guanosine monophosphate, implicated in several physiological and behavioural processes.

Binding of the cyclic <nucleotide> changes regulatory interactions and promotes catalytic activity toward selected <protein> <substrates>. This couples a <second messenger> to <phosphorylation>. A behavioural <phenotype> involving one family member does not establish an identical role for every cGMP-regulated kinase. <Enzyme Nomenclature by the IUBMB>[EC 2.7.11.12, cGMP-dependent protein kinase]{ref}