Chemotaxis feedback proteins (source code)

= Chemotaxis feedback proteins

<Chemotaxis feedback proteins> alter the internal signalling state of a chemotactic <cell> in response to pathway activity. In the canonical <Escherichia coli> system, <CheR> adds <receptor> <methyl groups> and <CheB> removes them, with <CheB> activity coupled to <phosphorylation>. Their opposing actions help restore receptor-pathway output after a persistent stimulus. This changes response sensitivity while allowing continued detection of subsequent changes in attractant <concentration>. <Robustness in simple biochemical networks by Naama Barkai and Stanislas Leibler>[1997, methylation-demethylation feedback architecture]{ref}