Clinical Global Impression–Improvement scale Created 2026-10-25 Updated 2026-11-05
The Clinical Global Impression–Improvement scale is a clinician’s ordered rating of change relative to a specified baseline. Its seven categories run from very much improved through no change to very much worse. It summarizes an overall judgment rather than measuring a fixed number of symptoms. In the childhood-anxiety trial, much or very much improved defined a treatment-response endpoint; that classification was distinct from establishing absence of every diagnosis or impairment. [ref]