= Comparative genomics
<Comparative genomics> compares <genomes> to identify shared sequences, lineage-specific changes and differences in <genome> organization. For example, conservation across related <species> can help identify a candidate regulatory element or evaluate a predicted <gene model>. Interpretation depends on shared ancestry and correct correspondence between regions: similarity can reflect <gene duplication> as well as common <species> ancestry. <Comparative Genomics Fact Sheet by NHGRI>[NHGRI, Comparative Genomics Fact Sheet: shared sequences, function and evolutionary relationships]{ref}
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