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Conditional front-door adjustment applies the front-door argument within strata of observed covariates and then averages over those covariates. The covariates must remove exposure-mediator confounding, while the exposure together with the covariates must remove mediator-outcome confounding.

WriteSince $X_1$ has no parents, its total effect has no backdoor path, and

For $X_2$, $X_3$ intercepts every directed path to $X_4$. Conditional on $X_1$, there is no unblocked backdoor path from $X_2$ to $X_3$, and $(X_1,X_2)$ blocks every backdoor path from $X_3$ to $X_4$. The conditional front-door adjustment therefore givesandPart ii shows that the inner sum, after also averaging $X_4$, does not actually depend on $x_1$.

For $X_3$, $(X_1,X_2)$ is a sufficient backdoor adjustment set. HenceThese three formulas identify the requested average treatment effects from the observed joint distribution.