DDM1 (source code)

= DDM1
{c}

A <nucleosome> remodeler that permits methyltransferase access to H1-containing <heterochromatin>.

Packaging into <nucleosomes> can restrict access to <DNA>. DDM1-dependent remodelling helps overcome that barrier, linking physical accessibility to the persistence of repressive methylation patterns in repeated genomic regions. <The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases to access H1-containing heterochromatin by Assaf Zemach and others>[2013, chromatin access and DNA methylation]{ref}