Dihydrofolate reductase
= Dihydrofolate reductase
<dihydrofolate reductase> catalyzes reduction of dihydrofolate to tetrahydrofolate using <NADPH>. Its catalytic cycle is a model for connecting <protein dynamics>, binding and release.<The dynamic energy landscape of dihydrofolate reductase catalysis by David D. Boehr and others>[pp. 1638–1642, dynamic states across the catalytic cycle]{ref}