= Discs large
<Discs large> denotes a conserved scaffold-protein family involved in organizing <cell> junctions, polarity and signalling complexes. Its interaction domains help assemble different partners at particular cellular locations. The original name comes from <mutant> <phenotypes> in <Drosophila> imaginal discs; related mammalian <proteins> have additional tissue-specific roles. A scaffold can influence a pathway by positioning components even without catalysing a <chemical reaction>. <NCBI Gene by the National Library of Medicine>[Homo sapiens, DLG1 record, Summary and linked functional evidence]{ref}
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