DNA-binding protein
= DNA-binding protein
A <DNA-binding protein> associates physically with <DNA>. Some recognize selected base patterns, while others preferentially recognize <DNA> shape, ends or damage. <Transcription factors> regulate expression, <histones> organize packaging and repair factors inspect damaged <substrates>. These roles illustrate why binding alone does not establish a specific regulatory outcome. Sequence selectivity, affinity and cellular occupancy are distinct measurable properties. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 4–7, DNA packaging, repair and regulation]{ref}