DNA hybridization
= DNA hybridization
{c}
<DNA hybridization> is association of nucleic-acid strands through complementary base pairing. It can form DNA-DNA or DNA-RNA duplexes, depending on the partners.
Sequence complementarity, temperature, ionic conditions, and strand concentration affect the equilibrium and rate of association. Mismatches can weaken binding, which makes hybridization useful for sequence-selective detection without making it an absolute all-or-nothing identity test.