= DNA replication inhibitor
{c}
A <DNA replication inhibitor> interferes with <DNA replication>; the observed effect depends on exposure and assay conditions.
Different compounds act at different steps: <hydroxyurea> limits precursor production, while <aphidicolin> inhibits selected replicative polymerases. Similar <reductions> in <DNA synthesis> can therefore have different molecular causes. Inhibition can also generate <replication stress>, so the resulting state differs from an unperturbed <cell> simply paused in time. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 5 and 17, DNA replication and replication control]{ref}
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