= DNA synthesis
<DNA synthesis> builds a <DNA> chain by forming <phosphodiester bonds> between <nucleotides>. In template-directed synthesis, a <DNA polymerase> extends a primer using <deoxynucleoside triphosphates>; chain extension proceeds in the $5^{\prime}$ to $3^{\prime}$ direction. <DNA replication> copies inherited information, while <DNA repair synthesis> fills material removed during repair. Chemical oligonucleotide synthesis uses different chemistry and need not rely on a polymerase or a template. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 5, DNA Replication Mechanisms; Chapter 8, DNA synthesis and manipulation]{ref}
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