DnaB (source code)

= DnaB
{c}

The conventional <E. coli> replicative <DNA helicase>, translocating on the lagging-strand template.

Unwinding supplies single-stranded templates to the replication machinery. Coupling the helicase to priming and synthesis limits uncontrolled separation of strands; helicase loading and an actively progressing fork are therefore distinct states. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 4–7, chromatin, replication and gene regulation]{ref}