ECT2 (source code)

= ECT2
{c}

A guanine-nucleotide exchange factor involved in local activation of <RhoA> during <animal> <cytokinesis>.

Spatially restricted <RhoA> activation helps organize the contractile machinery at the cleavage site. The exchange factor therefore links <positional information> from the division apparatus to local cytoskeletal <force> generation. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}