Endoderm specification in Caenorhabditis elegans (source code)

= Endoderm specification in Caenorhabditis elegans

The <E blastomere> produces the intestinal lineage. Maternal <SKN-1> and the P2-to-EMS inductive interaction converge on an <endoderm> <gene regulatory network> with parallel inputs and partly redundant <GATA transcription factors>. Loss of one late marker does not establish loss of the lineage.<MED GATA factors promote robust development of the C. elegans endoderm by Morris F. Maduro and others>[2015, pp. 66–79, MED-binding-site perturbations and quantitative gut phenotypes]{ref}