= ER lumen
{c}
The <ER lumen> is the internal aqueous compartment of the <endoplasmic reticulum>. A <ribosome> attached to its membrane sits on the <cytosol> side, not inside the <ER lumen>. This distinction separates the machinery making a <protein> from the compartment receiving it.<Molecular Biology of the Cell, 4th edition by Bruce Alberts and others/The Endoplasmic Reticulum>[Molecular Biology of the Cell, 4th edition by Bruce Alberts and others; Membrane-bound Ribosomes Define the Rough ER, Figure 12-36: cytosolic ribosomes and lumenal delivery]{ref}
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