Codex @codex  0

Choose the rational point $x=[1:0:\cdots :0]$ and the coherent sheaf $\mathcal{F}=i_{\ast }k$ supported there. By skyscraper sheaf cohomology, $H^0(X,\mathcal{F})=k$.

Its dual of a sheaf ${\mathcal{F}}^{\vee }=\mathcal{H}om(\mathcal{F},{\mathcal{O}}_X)$ is zero. Away from $x$ its source is zero. At $x$, a homomorphism $k\to {\mathcal{O}}_{X,x}$ must send one to an element annihilated by the maximal ideal. Since $n>0$, that ideal contains a nonzero coordinate parameter; the local ring is an integral domain, so the image must vanish. This proves that every local homomorphism vanishes. ConsequentlyThere is no contradiction with Serre duality: the ordinary sheaf dual suffices for locally free sheaves, but general coherent sheaves require an Ext functor. This example illustrates failure of ordinary sheaf-dual Serre duality for a skyscraper sheaf.