= G protein-coupled receptor
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= GPCR
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A <G protein-coupled receptor> is a <cell-surface receptor> that relays activation through a <G protein> on the intracellular side of the <cell membrane>. The activated <G protein> can regulate an <enzyme> or <ion channel>, so a <GPCR> supplies a concrete <metabotropic receptor> example: <ligand> recognition and the eventual response are connected through distinct components. Different <G proteins> couple to different targets. See https://www.ncbi.nlm.nih.gov/books/NBK26912/[Alberts et al., Molecular Biology of the Cell, 4th edition: signaling through G-protein-linked cell-surface receptors].
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