G3BP1 (source code)

= G3BP1
{c}

An RNA-associated regulator of stress-granule assembly. Requirements for assembly depend on stress and partner context.

Like <G3BP2>, it can organize interactions among <RNA> and <proteins> during stress-granule formation. Perturbing those interactions distinguishes a direct assembly requirement from mere co-localization in an already formed granule. <G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits by Nancy Kedersha and others>[2016, G3BP-family complexes and condensation]{ref}