GCN1 (source code)

= GCN1
{c}

A <ribosome>-associated regulator supporting activation of <GCN2> during nutrient stress.

Association with translating <ribosomes> links the signalling machinery to the state of <protein> synthesis. The response can reduce general initiation while favouring specific stress-regulated outputs, coupling nutrient availability to translational control. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}