= Gene model
A <gene model> is a structured representation of a <gene>, including its genomic location and proposed transcript structures. One model can include several splice isoforms with different <exon> combinations. Changing the reference sequence or adding <RNA sequencing> evidence can revise boundaries and coding predictions. The model represents current evidence and inference rather than a claim that every included transcript has been observed in every <tissue>. <Genomic annotation documentation by the National Library of Medicine>[Nucleotide sequence and genome annotation: gene models]{ref}
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