Genetic-study ascertainment (source code)

= Genetic-study ascertainment

= Ascertainment in a genetic study
{synonym}

<Ascertainment in a genetic study> specifies how individuals or families enter a genetic study. If $A$ is the event of inclusion, then $P(X\mid A)=P(X)P(A\mid X)/P(A)$. Selection on disease <phenotype> can change an unconditional <pedigree likelihood>. When comparing <genetic marker> <probabilities> conditional on a specified disease pattern, selection depending only on that pattern cancels from the linkage <likelihood ratio>.