= Genome assembly
<Genome assembly> reconstructs longer genomic sequences from shorter observations, such as sequencing <sequencing reads>. Overlap and long-range information help order and orient the pieces. Repeated sequences create ambiguity because a read may fit several locations; low coverage can leave gaps. An assembly is therefore an inferred representation with accuracy and completeness limits, and is distinct from <genome annotation>, which assigns features to that representation. <Talking Glossary of Genomic and Genetic Terms by NHGRI>[Genome Assembly entry]{ref}
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