= Gerald F. Joyce
{c}
<Gerald F. Joyce> coauthored work on generating genetic variation through error-prone <polymerase chain reaction>. Altering amplification conditions creates mutated copies that can be screened or selected, providing a source of variation for <directed evolution>.
The experimental distinction is between generating variation and selecting a useful molecular function: mutagenesis supplies candidates, while a separate assay determines which candidates meet the intended criterion.<Randomization of genes by PCR mutagenesis by R. Craig Cadwell and Gerald F. Joyce>[Research topic and author attribution in the primary publication]{ref}
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