= Gregory M. Greetham
{c}
= Greg Greetham
{c}
{synonym}
= G. M. Greetham
{c}
{synonym}
\b[Gregory M. Greetham], known professionally as \b[Greg Greetham], develops ultrafast spectroscopic instrumentation at the Central Laser Facility. His institutional profile describes work on the Ultra laser laboratories and their control systems, including <two-dimensional infrared spectroscopy> and <femtosecond stimulated Raman spectroscopy>.<Greg Greetham profile at the Central Laser Facility>[Professional background and Ultra development]{ref}
This instrumentation makes controlled <pump-probe spectroscopy> possible: one pulse initiates a change, and another probes the sample after a chosen delay. Pulse generation, timing, sample handling and acquisition all affect which molecular dynamics can be resolved. A faster probe alone cannot compensate for an initiating perturbation whose timing is poorly defined.
Greetham coauthored the2022 <RNA hairpin> refolding study, in which thin sample geometry enabled fast cooling as well as an initial <temperature jump>.<Measuring RNA UNCG Tetraloop Refolding Dynamics Using Temperature-Jump Drop Infrared Spectroscopy by C. P. Howe and others>[Byline; experimental description of sample geometry and cooling]{ref}
The study illustrates the scientific role of instrument design. Following recovery toward the starting structure requires the thermal perturbation to relax on a useful timescale; a setup that only heats quickly can obscure the later folding dynamics.
\Image[https://clf.stfc.ac.uk/wp-content/uploads/2025/10/05-Ultra-Team-Greg-Greetham-min.jpeg]
{title=Greg Greetham}
{id=image-greg-greetham-clf}
{description=Externally hosted profile photograph linked from the Central Laser Facility's named staff page.}
{width=250}
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