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Herbert G. Bull
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Herbert G. Bull
Created
2026-10-20
Updated
2026-11-05
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Herbert G. Bull
coauthored
research
on
finasteride
.
[ref]
Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP–Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor by Herbert G. Bull and others
. publication
title
and
author
list
Finasteride
is an unsaturated
4
-azasteroid inhibitor of
steroid
5α-reductase
.
Enzyme
-generated reduction and
enolate
capture of oxidized
cofactor
give
a
covalent
cofactor
–inhibitor
adduct
; the
protein
itself need not be covalently modified.
Total
articles
:
1