HSFA2 (source code)

= HSFA2
{c}

<HSFA2> is a heat-shock transcriptional regulator involved in sustained <stress responses> in <Arabidopsis thaliana>. Its role in <somatic stress memory> can outlast its direct occupancy of target regions.

Experiments found transient association of <HSFA2> with memory-related loci together with longer-lasting <histone methylation> and altered responses to a subsequent heat exposure. The distinction between the initial response and later memory is crucial: <HSFA2> dependence of the latter does not imply dependence of every immediate heat response.<A hit-and-run heat shock factor governs sustained histone methylation and transcriptional stress memory by Jörn Lämke and others>[Abstract, transient association and persistent H3K4 methylation]{ref}