= Joanne F. Berson
{c}
<Joanne F. Berson> led a 2001 study of how <Pmel17> helps form <premelanosomes>, the developing compartments in which <melanin> is deposited. The researchers followed processing and localization of the <protein>, then expressed it in nonpigmented <cells>. Expression alone initiated characteristic internal striations within <multivesicular bodies>.<Pmel17 initiates premelanosome morphogenesis within multivesicular bodies by Joanne F. Berson and others>[Abstract: post-Golgi processing and striation formation]{ref}
That reconstruction addressed causation more directly than finding <Pmel17> beside existing pigment: a normally nonpigmented <cell> acquired part of the specialized internal architecture after the <protein> was introduced. It established a role in compartment construction without implying that one <protein> recreates every step of pigment production.
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