MT1-MMP (source code)
= MT1-MMP
{c}
<MT1-MMP>, also called MMP14, is a membrane-associated metalloprotease involved in remodelling the <extracellular matrix>. Surface delivery concentrates proteolytic activity at particular cellular locations, linking <vesicle trafficking> to matrix interactions. Altered total <protein> abundance and altered delivery to the surface are different routes to changing extracellular activity. This distinction matters when relating a trafficking perturbation to <cell> invasion. <Syntaxin4-Munc18c Interaction Promotes Breast Tumor Invasion and Metastasis by Regulating MT1-MMP Trafficking by Megan I. Brasher and others>[MT1-MMP surface trafficking and invasion assays]{ref}
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