Nuclear retention (source code)

= Nuclear retention

<Nuclear retention> is persistence of a <molecule> inside the <cell nucleus> through binding, assembly or restricted export. For example, an incompletely processed <RNA> can remain nuclear while a mature transcript is exported. Nuclear enrichment can arise through faster import, slower export or binding to a nuclear component, so a static image alone does not identify the underlying rate change. <Nuclear retention> is a localization mechanism distinct from synthesis occurring only in the nucleus. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 12, The Transport of Molecules between the Nucleus and the Cytosol]{ref}