OPA1 (source code)

= OPA1
{c}

An inner-mitochondrial-membrane-associated regulator contributing to inner-membrane fusion and organization.

Its activity contributes to the organization of mitochondrial inner-membrane architecture, including cristae. Changes in <organelle> shape can therefore accompany changes in internal membrane organization; observing fragmented <mitochondria> alone does not identify which fusion or fission step changed. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}